' 
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.5
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Milk Thistle Seed 30:1 Extract(Silybum marianum) (Fruit/Seed) (80% [120 mg] Total Flavonoids)
150 mg
†
Top Medical Research Studies
9.5
2,3-dehydrosilybin shows heart protection
Cardioprotective effect of 2,3-dehydrosilybin preconditioning in isolated rat heart.
Relevant to heart disease research
We investigated the potential heart health benefits of 2,3-dehydrosilybin (DHS), a component of silybum marianum. In our study, rats' isolated hearts were treated with low doses of DHS before experiencing induced heart attacks and subsequent recovery.
The results showed that DHS significantly reduced heart tissue damage compared to untreated hearts, suggesting it has a protective effect. This effect is linked to specific signaling pathways in the heart. Overall, our research highlights the promising cardioprotective properties of this natural compound.
The results showed that DHS significantly reduced heart tissue damage compared to untreated hearts, suggesting it has a protective effect. This effect is linked to specific signaling pathways in the heart. Overall, our research highlights the promising cardioprotective properties of this natural compound.
Read More
9.5
Silybum marianum helps heart health
Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum.
High relevance based on findings.
We explored the potential of Silybum marianum (SM) in combating cardiac lipotoxicity following myocardial infarction (MI) in a pig study. Over 10 days, animals received either SM or a placebo.
The results showed that SM significantly lowered plasma triglyceride levels and reduced triglyceride absorption, leading to less fat accumulation in the heart muscle after ischemic injury.
Importantly, the SM treatment was free of side effects, indicating its promise as a supportive therapy for heart disease without adverse reactions.
The results showed that SM significantly lowered plasma triglyceride levels and reduced triglyceride absorption, leading to less fat accumulation in the heart muscle after ischemic injury.
Importantly, the SM treatment was free of side effects, indicating its promise as a supportive therapy for heart disease without adverse reactions.
Read More
9
Milk thistle aids heart recovery
Silybum marianum provides cardioprotection and limits adverse remodeling post-myocardial infarction by mitigating oxidative stress and reactive fibrosis.
Highlights cardiac healing potential
We explored how Silybum marianum, or milk thistle, can affect heart health, especially after a heart attack. In studies on pigs, we found that giving SM shortly before and after a heart attack helped reduce damage and improve recovery.
It showed potential in lowering oxidative stress and enhancing heart function. However, animals with no heart attack didn't experience these benefits. Our findings suggest that milk thistle could play a role in heart recovery during critical phases following a heart attack.
It showed potential in lowering oxidative stress and enhancing heart function. However, animals with no heart attack didn't experience these benefits. Our findings suggest that milk thistle could play a role in heart recovery during critical phases following a heart attack.
Read More
Most Useful Reviews
8.8
Reduces bad cholesterol
Milk thistle helps to lower bad cholesterol (LDL), which in turn protects against heart disease. It can be taken alongside cholesterol medications, due to its beneficial effects on liver health, as liver issues are a known side effect of these medications.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.5
- All Researches
9.5
Silybum marianum helps heart health
Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum.
High relevance based on findings.
We explored the potential of Silybum marianum (SM) in combating cardiac lipotoxicity following myocardial infarction (MI) in a pig study. Over 10 days, animals received either SM or a placebo.
The results showed that SM significantly lowered plasma triglyceride levels and reduced triglyceride absorption, leading to less fat accumulation in the heart muscle after ischemic injury.
Importantly, the SM treatment was free of side effects, indicating its promise as a supportive therapy for heart disease without adverse reactions.
The results showed that SM significantly lowered plasma triglyceride levels and reduced triglyceride absorption, leading to less fat accumulation in the heart muscle after ischemic injury.
Importantly, the SM treatment was free of side effects, indicating its promise as a supportive therapy for heart disease without adverse reactions.
Read More
9.5
2,3-dehydrosilybin shows heart protection
Cardioprotective effect of 2,3-dehydrosilybin preconditioning in isolated rat heart.
Relevant to heart disease research
We investigated the potential heart health benefits of 2,3-dehydrosilybin (DHS), a component of silybum marianum. In our study, rats' isolated hearts were treated with low doses of DHS before experiencing induced heart attacks and subsequent recovery.
The results showed that DHS significantly reduced heart tissue damage compared to untreated hearts, suggesting it has a protective effect. This effect is linked to specific signaling pathways in the heart. Overall, our research highlights the promising cardioprotective properties of this natural compound.
The results showed that DHS significantly reduced heart tissue damage compared to untreated hearts, suggesting it has a protective effect. This effect is linked to specific signaling pathways in the heart. Overall, our research highlights the promising cardioprotective properties of this natural compound.
Read More
9
Milk thistle aids heart recovery
Silybum marianum provides cardioprotection and limits adverse remodeling post-myocardial infarction by mitigating oxidative stress and reactive fibrosis.
Highlights cardiac healing potential
We explored how Silybum marianum, or milk thistle, can affect heart health, especially after a heart attack. In studies on pigs, we found that giving SM shortly before and after a heart attack helped reduce damage and improve recovery.
It showed potential in lowering oxidative stress and enhancing heart function. However, animals with no heart attack didn't experience these benefits. Our findings suggest that milk thistle could play a role in heart recovery during critical phases following a heart attack.
It showed potential in lowering oxidative stress and enhancing heart function. However, animals with no heart attack didn't experience these benefits. Our findings suggest that milk thistle could play a role in heart recovery during critical phases following a heart attack.
Read More
8
Silymarin shows protective effects
Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress.
Moderately relevant findings presented
We explored the effects of silymarin on heart and liver health in a study involving 28 male mice. The animals were divided into groups and treated with silymarin, saline, and paracetamol to simulate oxidative stress.
The results showed that silymarin significantly reduced liver damage and inflammation caused by paracetamol and also demonstrated protective effects in cardiac tissue. While these findings highlight its potential as a treatment for heart and liver issues, further research is needed to confirm how effective silymarin is in humans.
The results showed that silymarin significantly reduced liver damage and inflammation caused by paracetamol and also demonstrated protective effects in cardiac tissue. While these findings highlight its potential as a treatment for heart and liver issues, further research is needed to confirm how effective silymarin is in humans.
Read More
8
Silybum marianum's effects on heart injury
Silymarin component 2,3-dehydrosilybin attenuates cardiomyocyte damage following hypoxia/reoxygenation by limiting oxidative stress.
Moderate relevance for heart disease
We explored how 2,3-dehydrosilybin (DHS), a component of Silybum marianum, may protect heart cells from damage caused by a lack of oxygen. The study involved cultured rat heart cells subjected to hypoxia and reoxygenation, which is a common stress for heart tissue. Our findings revealed that while DHS treatment reduced the harmful production of reactive oxygen species, it did not improve cell viability. Thus, while DHS offers some protective effects, significant benefits for heart health remain unconfirmed.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Reduces bad cholesterol
Milk thistle helps to lower bad cholesterol (LDL), which in turn protects against heart disease. It can be taken alongside cholesterol medications, due to its beneficial effects on liver health, as liver issues are a known side effect of these medications.
